Endomimetics™ is committed to transforming the quality of patient care by enhancing the safety and performance of surgical and implantable medical devices. Using our proprietary Bionanomatrix technology, there is tremendous opportunity to improve procedural and post-implantation device healing, performance, and safety. Our mission is to develop healing solutions that reduce complications, minimize repeat procedures, and boost the functionality of medical implants.
Founded by physician-scientists from the University of Alabama at Birmingham
Technologies that conform to rigorous quality and safety standards.
Pioneers in bioengineering solutions for medical device challenges.
Bionanomatrix™ is a groundbreaking peptide-based coating or gel designed for a wide range of medical applications. This technology improves tissue integration, accelerates healing, and extends the lifespan of implants for procedures. By reducing the risk of adverse reactions, Bionanomatrix significantly boosts patient outcomes and the effectiveness of medical treatments.
Engineered to meet the specific requirements of different medical devices, including cardiovascular, orthopedic, and general surgical implants, Bionanomatrix can be tailored to support a wide range of medical needs. Additionally, our gel formulation promotes healing of surgical sites such as created vascular access points which have a high failure rate.
The technology promotes acceptance of medical implants by the body, minimizing the immune response and significantly lowering the risk of rejection. It is natural, free of organic solvents, and has anti-inflammatory benefits.
Designed to prolong the functional life of medical implants, our coatings support optimal healing, encourage cell growth, and facilitate quick recovery.
Bionanomatrix™ helps prevent common complications such as post-operative infections, restenosis, and improper healing. The nanomatrix releases nitric oxide (NO) to arrest neointimal proliferation, stimulate endothelialization, reduce inflammatory responses, and inhibit thrombogenesis. NO also provides other beneficial effects, including vasodilation, smooth muscle cell migration and proliferation, and platelet activation.
The versatility of the Bionanomatrix™ technology lends itself to applications that span multiple medical disciplines. As a result, it has the potential to create a far-reaching impact on patient care.
At Endomimetics, we're excited to push the boundaries of cardiovascular health with our innovative Bionanomatrix™ technology. Designed for use in vascular grafts and stents, this technology helps reduce the risk of thrombosis and promotes healing, in turn improving the outcomes of heart and vascular procedures.
The Bionanomatrix™ AVF Gel Formulation is designed to greatly improve the maturation of the preferred vascular access for dialysis - arteriovenous fistulas (AVFs), which have a 60% failure rate - by improving vasodilation, enhancing healthy healing, and limiting neointimal hyperplasia.
The Bionanomatrix™ coating is designed to infuse knee implants with nitric oxide and antibiotics, preventing infections and reducing scarring that can impair implant function and movement.
In partnership with BISCO, Inc., we are utilizing our Bionanomatrix™ technology in order to develop state-of-the-art materials for direct pulp capping and enhance dental device integration to combat peri-implantitis. We are dedicated to advancing dental technologies that set new standards in care and dramatically improve patient outcomes.
Our groundbreaking Bionanomatrix™ coating is designed to revolutionize the treatment of brain aneurysms by accelerating healing on flow diverters, and brain aneurysm occluders, significantly reducing the risk of blood clots and reliance on risky blood-thinning medications. Thus, it not only promises to save lives but also to restore peace of mind to patients and their families.
Meet the Endomimetics team, a group of dedicated professionals committed to advancing medical technology and improving patient care. Our leadership combines decades of expertise in biomedical engineering, bioinformatics, and healthcare innovation.
Explore the latest updates on our research, product developments, and partnerships. Additionally, get access to expert insights in the field of bioengineering.
